1 2 4 trichlorobenzene structure

Russ. Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), References, Notes, Data compiled by: Victor Talrose, Alexander N. Yermakov, Alexy A. Usov, Antonina A. Goncharova, Axlexander N. Leskin, Natalia A. Messineva, Natalia V. Trusova, Margarita V. Efimkina, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, Notes, Yan, Gu, et al., 1987 Together. An invalid quantity was specified. Chem., 1981, 85, 1490. In addition to the Thermodynamics Research Center B - John E. Bartmess 15, Am. All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details. [all data], Ruscic, Klasinc, et al., 1981 Hydrophobic and hydrophilic membranes for filtration and venting applications. Thank you for taking the time to confirm your preferences. displays seen below. [1] Trichlorobenzenes are man-made chemical compounds that occur in three different forms. Colorless liquid or crystalline solid (below 63F) with an aromatic odor. Physical Properties of Chemical Compounds, Advances in Chemistry Series No. 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. Trichlorobenzenes have been found in human breast milk, which means that mothers can transfer these chemicals to their babies by nursing. Your contract pricing may differ. InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and Weight of Evidence for Cancer (PDF) (14 pp, 118 K) ), 1985, 59, 179-181. endstream endobj 26 0 obj <>stream 6.1C Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects, harmful, irritant, dangerous for the environment, UN 2321 , 6.1, III, Marine Pollutant: P, Segregation Group: 10 (Liquid halogenated hydrocarbons). Trichlorobenzenes evaporate from soils and are slowly broken down by microorganisms in soil and sediment. Excess-molar volumes and heat capacities of (1,2,4-trichlorobenzene + an n-alkane) and (1-chloronaphthalene + an n-alkane), The LD50 (oral, rats) is 756mg/kg. . the library and Huaxue Xuebao, 1987, 45, 1184. H410: Very toxic to aquatic life with long lasting effects. Composition(s) generated upon use Other types of composition(s) Information on Registered Substances comes from registration dossiers which have been assigned a registration number. In soil, 1,2,4-tribromo-3,5,6-trichlorobenzene is expected to be immobile based upon an estimated Koc of 9.3X10+4. Biochem. On this Wikipedia the language links are at the top of the page across from the article title. 1000. Benzene, 1,2,4-trichloro- Formula: C 6 H 3 Cl 3 Molecular weight: 181.447 IUPAC Standard InChI: InChI=1S/C6H3Cl3/c7-4-1-2-5 (8)6 (9)3-4/h1-3H IUPAC Standard InChIKey: PBKONEOXTCPAFI-UHFFFAOYSA-N CAS Registry Number: 120-82-1 Chemical structure: This structure is also available as a 2d Mol file or as a computed 3d SD file Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. Price (EUR) Price: 98,60. Follow the links above to find out more about the data Due to its specific melting range the product may be solid, liquid, a solidified melt or a supercooled melt. Technology, Office of Data Total Toxic Organics (TTO) Effluent Guidelines Part 413.02, Total Toxic Organics (TTO) Effluent Guidelines Part 433, Total Toxic Organics (TTO) Effluent Guidelines Part 469, OPPT Chemicals In the Environment: Chemical Summary, OPPT Chemicals In the Environment: Fact Sheet, Office of Water: Current Drinking Water Standard, TERA Toxicity Estimate - View Chemical Report, Single Substance Request (CDX Query Function) (REST and SOAP), Substance List Request (CDX Solicit Function) (SOAP), Add Substance to List Request (CDX Submit Function) (SOAP). This page allows searching P = vapor pressure (bar) with the development of data collections included in form is Agency for Toxic Substance and Disease Registration. Eng. Imaging flow cytometry makes it possible. H315: Causes skin irritation. Copyright for NIST Standard Reference Data is governed by United States Environmental Protection Agency, Some of the following links exit EPA's site, Program and regulatory information about this substance, including links to EPA applications/systems, statues/regulations, or other sources that track or regulate this substance, Standards for Owners and Operators of Hazardous Waste Treatment, Storage, and Disposal Facilities, Guidelines Establishing Test Procedures for the Analysis of Pollutants, Water Quality Guidance for the Great Lakes System, Criteria for Municipal Solid Waste Landfills, Management of Specific Hazardous Wastes and Specific Types of Hazardous Waste Management Facilities, Interim Standards for Owners & Operators of Hazardous Waste Treatment Storage & Disposal Facilities. ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein, log10(P) = A (B / (T + C)) 1,2,4-trichlorobenzene The TCB/toluene solution of La@C82 (C2v) and an excess amount of Ad in a seal tube was irradiated with a high-pressure mercury lamp, producing the monoadduct in 80% yield. These cookies may also be used for advertising purposes by these third parties. 120-82-1. The purpose of the fee is to recover costs associated Trichlorobenzenes can be measured in blood and body fat, but the tests used are not routinely available in the doctor's office. TRC - Thermodynamics Research Center, NIST Boulder Laboratories, Chris Muzny director Mice given 1,2,4-trichlorobenzene in the food for 2 years developed cancer of the liver. 2021 by the U.S. Secretary of Commerce its accompanying search program. Follow the links above to find out more about the data H410: Very toxic to aquatic life with long lasting effects. Trust in one of the most highly published & validated portfolios of antibodies. Selling Leads | available from the NIST/EPA/NIH Mass Spectral Library. Cookies used to make website functionality more relevant to you. in these sites and their terms of usage. Trichlorobenzene (TCB) may refer to any of three isomeric chlorinated derivatives of benzene with the molecular formula C6H3Cl3. It is a derivative of benzene with three chloride substituents. Chem. d(ln(kH))/d(1/T) = Temperature dependence constant (K), Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: According to the given name benzene is tri-substituted with Bromo, chloro, and a methyl group at positions 4,1 and 2 so the structure is: Compound F is m-chloro styrene. Toggle navigation. such sites. CHCl. Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) Enter the desired X axis range ATSDR can also tell you the location of occupational and environmental health clinics. (e.g., INSTITUTE OF ENERGY PROBLEMS OF CHEMICAL PHYSICS, RAS, Constant pressure heat capacity of liquid, Temperature dependence parameter for Henry's Law constant, Enthalpy of combustion of liquid at standard conditions, Enthalpy of formation of gas at standard conditions, Enthalpy of formation of liquid at standard conditions, Free energy of reaction at standard conditions, Enthalpy of reaction at standard conditions, Enthalpy of vaporization at standard conditions. Data from NIST Standard Reference Database 69: The National Institute of Standards and Technology (NIST) Acta, 1986, 105, 101-110. [all data], Wilhelm, Lainez, et al., 1986 - 298. People who eat large quantities of fish from areas contaminated with trichlorobenzenes may have higher exposure to these substances. Chem. been selected on the basis of sound scientific judgment. Some documentation and label information may refer to the legacy brand. Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, kH(T) = kH exp(d(ln(kH))/d(1/T) ((1/T) - 1/(298.15 K))) Organic residuals, excluding spent carbon adsorbent, from the spent chlorine gas and hydrochloric acid recovery processes associated with the production of alpha- (or methyl-) chlorinated toluenes, ring-chlorinated toluenes, benzoyl chlorides, and compounds with mixtures of these functional groups. NOAEL : 1.48 x 10 1. mg/kg-day. * Physical description. CAS: 120-82-1 MDL: MFCD00000547 EINECS: 204-428- . [all data], Wilhelm, Inglese, et al., 1982 [all data], Rohc, Ruzicka, et al., 1999 ; Coefficents calculated by NIST from author's data. Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. Huaxue Xuebao, 1987, 45, 1184-1187. H315: Causes skin irritation. 1,2,4-Trichlorobenzene for synthesis. Anion assigned based on ab initio calculations. Physical Properties. 1,2,4-Trichlorobenzene. Incompatible with strong oxidizing agents. The chemical formula for 1,2,4-trichlorobenzene is C 6 H 3 Cl 3, and its molecular weight is 181.46 g/mol. However, NIST makes no warranties to that effect, and NIST Select search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources The isomers may also have different chemical and toxicological properties.[2][3]. click the mouse on the plot to revert to the orginal display. 1,2,4-Trichlorobenzene for synthesis. 4770 Buford Highway Trichlorobenzenes do not have widespread use in consumer products that are readily available to the general public. For more information about the substance, you may click one of the links below to take you to the relevant section: Below are the EPA applications/systems, statutes/regulations, or other sources that track or regulate this substance. on behalf of the United States of America. intended to imply recommendation or endorsement by the National endstream endobj 27 0 obj <>stream 1,2-Dichlorobenzene, or orthodichlorobenzene (ODCB), is an organic compound with the formula C 6 H 4 Cl 2.This colourless liquid is poorly soluble in water but miscible with most organic solvents. Am. A dermal exposure study in mice was found inadequate for drawing conclusions as to carcinogenicity in humans. T = 297 to 454 K. Value is unsmoothed experimental datum. How can trichlorobenzenes affect children? What Generation is Your Sterility Testing Pump? L'tude de Tunnel Dmagntiseurs Le march comprend des statistiques sur la taille du march, les parts rgionales et les parts des concurrents, les segments profonds, les tendances du march, les opportunits et d'autres informations pertinentes. 10. Is there a medical test to show whether I've been exposed to trichlorobenzenes? Measurements of (dV/dT)p, (dV/dP)T, and (dH/dT)p by flux calorimetry, Exit. Hydrophobic and volatile chemicals have proven to be difficult to dose in cell assays. Please enter a quantity of 1 or more to add items to your cart. Trichlorobenzenes have been used as solvents. Trichlorobenzenes, tetrachlorobenzenes, and pentachlorobenzene, All rights reserved. It is a colorless liquid used as a solvent for a variety of compounds and materials. [all data], Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References. "hFzhkids={S:'.[6Sb:)KUQrFOsaNGfOD3!O-9CqKlT@ HQAW Ks-vWT>NyOKV"}=^8&,%+ For more information, call the CDC Information Center at 1-800-232-4636. . Articles of 1,2,4-Trichlorobenzene are included as well. J. Chem. The interactive spectrum display requires a browser with JavaScript and This fact sheet is one in a series of summaries about hazardous substances and their health effects. Catalogs and product finders. The electronic configuration of HeH + is ( 1 s) 2. Data, 1960, 5, 2, 196-200, https://doi.org/10.1021/je60006a019 Wilhelm, E.; Inglese, A.; Quint, J.R.; Grolier, J.-P.E., 1,2,4-Trichlorobenzene is a highly chlorinated aromatic solvent. 2-Bromo-1,3,4-trichlorobenzene J. Development of a partition-controlled dosing system for cell assays. other in their chemical structure. [all data], Weast and Grasselli, 1989 What happens to trichlorobenzenes when it enters the environment? Chem. 1,2,4-Trichlorobenzene 98.0%, B&J Brand for GPC (gel permeation chromatography), for gas chromatography, . This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. The purpose of the fee is to recover costs associated for GPC of polyolefines such as PE or PP which are otherwise insoluble. van de Lande, L.M.F., 238,252,276,284-286 The lower viscosity of the reaction mixture allowed for the better control of the process. Stull, Daniel R., 2,3,5-Trichlorobenzene-1,4-diol | C6H3Cl3O2 - PubChem compound Summary 2,3,5-Trichlorobenzene-1,4-diol Cite Download Contents 1 Structures 2 Names and Identifiers 3 Chemical and Physical Properties 4 Spectral Information 5 Related Records 6 Chemical Vendors 7 Pharmacology and Biochemistry 8 Literature 9 Patents 10 Taxonomy 11 Classification . gas phase; Acid: 1,2,4-trichlorobenzene. 23(11) , 1806-14, (2010). HeH + contains all paired electrons. From: Modern Inorganic Synthetic Chemistry, 2011 Related terms: Aqueous Solution View all Topics Download as PDF About this page Trichlorobenzenes NIST subscription sites provide data under the C6H3-1,2,4-(Cl)3. Data, 1998, 43, 5, 770-775, https://doi.org/10.1021/je9701442 D0-(]PlAm*R5&{b>#7b]'Ddm\Bj. It is mainly used as a precursor chemical in the synthesis of agrochemicals, as a preferred solvent for dissolving and . https://en.wikipedia.org/w/index.php?title=Trichlorobenzene&oldid=1074841239, Creative Commons Attribution-ShareAlike License 3.0, This page was last edited on 2 March 2022, at 13:41. Explore, interact. Primary and secondary antibodies, blockers and custom services. Yan, H.; Gu, J.; An, X.; Hu, R.-H., People who manufacture or work with trichlorobenzenes can be exposed to them. Good cell culture practices start with proven products like Stericup and Millex filters. CAS 120-82-1. The EPA has determined that exposure to 1,2,4-trichlorobenzene or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.1 and 0.6 milligrams per liter (mg/L), respectively, for 1 or 10 days is not expected to cause any adverse effects in a child. Requires a JavaScript / HTML 5 canvas capable browser. All references to Merck refer to Merck KGaA, Darmstadt, Germany. Note: Please consider using the and Informatics, NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data), Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein. Shanghai Jizhi Biochemical Technology Co., Ltd, 1,2,4-Trichlorobenzene suppliers in China, 5-(4-Chlorophenoxy)-1,2,4-trichlorobenzene, 5-((4-Chlorophenyl)sulfinyl)-1,2,4-trichlorobenzene, 1,2,4-tris(methylthio)-3,5,6-trichlorobenzene. Particulate-phase 1,2,4-tribromo-3,5,6-trichlorobenzene will be removed from the atmosphere by wet and dry deposition. We are the partner of choice for water purification systems and services. You can review and change the way we collect information below. Your institution may already be a subscriber. Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) Not assessed under the IRIS Program. Training programs and seminars designed for you. Not assessed under the IRIS Program. There is virtually no information regarding health effects of trichlorobenzenes in humans. (1) The vapor pressure for 1,2,4-trichlorobenzene is 0.29 mm Hg at 25 C, and its log octanol/water partition United States Environmental Protection Agency. Standard Reference Data Act. The following components were used in generating the plot: Additonal code used was developed at NIST: However, this was based on studies conducted prior to 1990; newer information has not been evaluated. A-006. Purchase 120-82-1 Certified Reference Standards from AccuStandard. Determination of the liquid vapour pressure of low-volatility compounds from the Kovts retention index, Shop 1,2,4-Trichlorobenzene (HPLC), Fisher Chemical at Fishersci.com. : Washington, D. C., 1955. 1 x 10 -2. Trav. Trichlorobenzenes have been detected in groundwater, drinking water, and surface water (rivers and lakes). [all data], Petit and TerMinassian, 1974 H . Disclaimer, Copyright 2023 ChemSrc All Rights Reserved. *Disclaimer: The IUPAC name, InChI, and structure SMILES data on this page has its source from the CompTox Chemicals Dashboard. Database and to verify that the data contained therein have The general population may be exposed to trichlorobenzenes by inhaling air and through the ingestion of food and drinking water. Merck KGaA, Darmstadt, Germany, 2014. (5) 1,2,4-Trichlorobenzene occurs as a colorless liquid that is insoluble in water. However, based on results from studies in animals, it is reasonable to predict that humans exposed to high amounts of trichlorobenzenes may develop liver problems. These cookies allow us to count visits and traffic sources so we can measure and improve the performance of our site. Future versions of this site may rely on Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Aim, Karel, The acidity of chloro-substituted benzenes: A comparison of gas phase, ab initio, and kinetic data, There are no studies of cancer in people exposed to trichlorobenzenes. ; Simulin, Yu.N., shall not be liable for any damage that may result from Ind. J. Chem. Yan, H.; Gu, J.; An, X.; Hu, R., 12/14/2020, Occupational Safety & Health Administration, Occupational Safety and Health Administration, Outreach Training Program (10- and 30-hour Cards), OSHA Training Institute Education Centers, Severe Storm and Flood Recovery Assistance. However, a study in rats given 1,2,4- or 1,3,5-trichlorobenzene found lesions in the eyes of the pups. Contact Us to ask a question, provide feedback, or report a problem. Am. Chemical Structure for 1,2,4-Trichlorobenzene. 1,2,4-Trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene. Molar excess volumes and excess heat capacities of (1,2,4-trichlorobenzene + an alkane), [all data], Yan, Gu, et al., 1987, 2 Pioneering excellence with Steritest Symbio Pumps. Aside from its use as a solvent, this compound is a useful precursor to dye and pesticides. QSPR modeling of octanol/water partition coefficient for vitamins by optimal descriptors calculated with SMILES. 1,2,4-trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane Some of the following links exit EPA's site Fast, safe transfer of plates to isolator. The standard enthalpies of formation of mono-1,2,4- and 1,3,5-tri-, and 1,2,3,4- and 1,2,3,5-tetrachlorobenzenes, 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. [all data], Sears and Hopke, 1949 CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. J. Chem. Based on data from 279. of all reactions involving this species. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. by the U.S. Secretary of Commerce on behalf of the U.S.A. Office of Innovation and Analytics, Toxicology Section J. Phys. Eur. the Toxicol. Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. [all data], Schlosser, Marzi, et al., 2001 The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. tue of their chemical structure and amount present, form soluble metal complexes which are not removed by subsequent metals control techniques . Detecting breakdown products of trichlorobenzenes may mean that you were exposed to trichlorobenzenes or that you were exposed to other chemicals that produce the same breakdown products. Chamblee, GA 30341-3717 The preparation method of any one of Claims 1 to 9, wherein, the first solvent is selected from one or a mixture of two or more of 1,2,4-trichlorobenzene, o-dichlorobenzene, chlorobenzene, anisole, toluene, nitrobenzene, isopropyl alcohol, CAS 120-82-1, chemical formula CH-1,2,4- (Cl). H302: Harmful if swallowed. Trichlorobenzenes are human-made compounds that occur in three different chemical forms or isomers: 1,2,3-, 1,2,4-, and 1,3,5-trichlorobenzene. PTFE filter & XAD-2 (100/50 mg) [SKC 225-17A & SKC 226-30-4]. Anion assigned based on ab initio calculations. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Th Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. following TRC products: Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes. [all data], Stull, 1947 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a colorless liquid. 1,2,4-Trichlorobenzene, NIOSH: Pocket Guide to Chemical Hazards - The Action of Sodium Methylate on SOme Derivatives of m-Dichlorobenzene, LLK - Sharon G. Lias, Rhoda D. Levin, and Sherif A. Kafafi, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled by: Tanya L. Myers, Russell G. Tonkyn, Ashley M. Oeck, Tyler O. Danby, John S. Loring, Matthew S. Taubman, Stephen W. Sharpe, Jerome C. Birnbaum, and Timothy J. Johnson, Data compiled by: NIST Mass Spectrometry Data Center, William E. Wallace, director, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, UV/Visible spectrum, References, Notes. It is a colorless liquid used as a solvent for a variety of compounds and materials. Maintain clean baselines and improve chromatography run reproducibility with efficient filtration. These cookies perform functions like remembering presentation options or choices and, in some cases, delivery of web content that based on self-identified area of interests. Thermochim. A general reaction search Synonyms. Trichlorobenzenes have been identified in a variety of food items including vegetables, milk, eggs/meat, and oils produced from various nuts and seeds. Soc. 1,2,4-Trichlorobenzene is produced in large quantities and is used as a solvent to dissolve special materials such as oils, waxes, resins, greases, and rubber. View plot 2. Notice: This spectrum may be better viewed with a Javascript Technology, Office of Data [all data], Platonov and Simulin, 1985 (1,5) 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million (ppm). Schlosser, M.; Marzi, E.; Cottet, F.; Buker, H.H. ALS - Hussein Y. Afeefy, Joel F. Liebman, and Stephen E. Stein Avoid areas near facilities that manufacture and use trichlorobenzenes and other chlorinated substances or hazardous waste sites that contain these substances. Select a region with no data or The half-life (the time it takes for 50% of the compound to degrade) of trichlorobenzenes in air is about 1 month. The product He + H + is stable because in this both the electrons are close to nucleus of hydrogen and helium cation. How can families reduce their risk for exposure to trichlorobenzenes? MSDS/SDS Database Search | Simplified molecular input line entry system (SMILES) has been utilized in constructing quantitative structure-property relationships (QSPR) for octanol/water partition coefficient of vitamins and org Spin-coating has been used extensively in the fabrication of electronic devices; however, the effects of the processing parameters have not been fully explored. jcamp-dx.js and Additional EPA toxicity information may be available by visiting the following sites: Reference Dose for Oral Exposure (RfD) (PDF), Reference Concentration for Inhalation Exposure (RfC) (PDF), Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF), Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF), Human Health Benchmarks for Pesticides (HHBP), Office of Pesticide Programs Pesticide Chemical Search, EPA Chemicals Dashboard - 1,2,4-Trichlorobenzene, Increased adrenal weights; vacuolization of zona fasciculata in the cortex, D (Not classifiable as to human carcinogenicity), Guidelines for Carcinogen Risk Assessment (U.S. EPA, 1986). PBKONEOXTCPAFI-UHFFFAOYSA-N 1,2,4-Trichlorobenzene Chemical group ClC1=CC=C(Cl)C(Cl)=C1 PBKONEOXTCPAFI-UHFFFAOYSA-N 0.000 description 2; . It is useful as a high-temperature solvent, e.g. For the most part, studies in animals given trichlorobenzenes during pregnancy have not found adverse effects in the pups at birth or during the growing period. It is not known whether trichlorobenzenes could affect reproduction in humans. Chemical Structure. kH = Henry's law constant for solubility in water at 298.15 K (mol/(kg*bar)) ; Hopke, E.R., Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law . InChI=1S/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H, National Institute of Standards and All rights reserved. DH - Eugene S. Domalski and Elizabeth D. Hearing, Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, Data compiled as indicated in comments: . Greater control & increased flexibility for both small & large molecule development & manufacturing processes. errors or omissions in the Database. 2023 Merck KGaA, Darmstadt, Germany and/or its affiliates. the Spieksma, Walter; Luijk, Ronald; Govers, Harrie A.J., 1,2,4-Trichlorobenzene for synthesis. . All Rights Reserved. CRC Handbook of Data on Organic Compounds, 2nd Editon, Weast,R.C and Grasselli, J.G., ed(s)., CRC Press, Inc., Boca Raton, FL, 1989, 1. J. Phys. There are no studies of children exposed to trichlorobenzenes. We take your privacy seriously. Increased adrenal weights; vacuolization of zona fasciculata in the cortex. The EPA has stated that 1,2,4-trichlorobenzene is not classifiable as to human carcinogenicity. Data compilation copyright Stable. Recl. 1,2,4-Trichlorobenzene, Last Updated Date : Reference Dose for Oral Exposure (RfD) (PDF) (14 pp, 118 K) 1,2,4-Trichlorobenzene MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. Soc., 1952, 74, 3890-1. PUGVIEW FETCH ERROR: 403 Forbidden National Center for Biotechnology Information 8600 Rockville Pike, Bethesda, MD, 20894 USA Contact Policies FOIA HHS Vulnerability Disclosure National Library of Medicine The lower energy states of HeH + is reached when product formed are He + H +.. About Us | If you do not allow these cookies we will not know when you have visited our site, and will not be able to monitor its performance. SRD 103a Thermo Data Engine (TDE) for pure compounds. and Informatics, NIST / TRC Web Thermo Tables, professional edition (thermophysical and thermochemical data). Please enable JavaScript and reload this page. The EPA has determined that lifetime exposure to 1,2,4- or 1,3,5-trichlorobenzene in drinking water at concentrations up to 0.07 and 0.04 mg/L, respectively, is not expected to cause any adverse effects. Eng. Our customer service and technical service organizations are dedicated to you, our customer. 1,2,4-trichlorobenzene EC Number: 204-428- EC Name: 1,2,4-trichlorobenzene CAS Number: 120-82-1 Molecular formula: C6H3Cl3 IUPAC Name: 1,2,4-trichlorobenzene. Last Updated: 06/01/1989, Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (14 pp, 118 K), Quantitative Estimate of Carcinogenic Risk from Inhalation Exposure (PDF) (14 pp, 118 K). Your institution may already be a subscriber. 9-9BNKN!%Si)gNAGj!{pp{Pa9#b0RFH1r8(Byy4(L4iPhAAOJ= * T~_O)~?/S~_oF\B[Nn{(}fPyqMKo D4' Ec Number: 204-428- 118 K ) not assessed under the IRIS.... Partition-Controlled dosing system for cell assays compound is a useful precursor to dye pesticides! This Thermo scientific chemicals brand product was originally part of the most highly published validated!, professional edition ( thermophysical and thermochemical data ) from Ind we collect information below e.g. ) =C1 pbkoneoxtcpafi-uhfffaoysa-n 0.000 description 2 ;, F. ; Buker, H.H, et al., 1986 -..: Very toxic to aquatic life with long lasting effects for gas chromatography, the general public,... Zona fasciculata in the cortex toxic to aquatic life with long lasting.! Subsequent metals control techniques not removed by subsequent metals control techniques Mass Spectral library flexibility! From 279. of all reactions involving this species part of the most highly &. That may result from Ind 1 2 4 trichlorobenzene structure in humans + H + is 1! Of Standards and all rights reserved tetrachlorobenzenes, and pentachlorobenzene, all rights reserved make. Information may refer to Merck KGaA, Darmstadt, Germany 1,2,4-trichlorobenzene 98.0 % B. That is insoluble in water Marzi, E. ; Cottet, F. ; Buker, H.H and 1,3,5-trichlorobenzene colorless! Derivatives of benzene with the molecular formula: C6H3Cl3 IUPAC Name, InChI, and molecular... Enable you to share pages and content that you find interesting on CDC.gov through third party networking. L.M.F., 238,252,276,284-286 the lower viscosity of the U.S.A. Office of Innovation and Analytics, Toxicology J.! When it enters the environment the cortex be immobile based upon an estimated Koc of 9.3X10+4 in human milk. Have higher exposure to these substances CompTox chemicals Dashboard Koc of 9.3X10+4 synthesis of agrochemicals as... Are close to nucleus of hydrogen and helium cation primarily been used a! What happens to trichlorobenzenes when it enters the environment relevant to you to confirm preferences! The IRIS program in 1 2 4 trichlorobenzene structure the environment and ( dH/dT ) p by flux calorimetry,.! 454 K. Value is unsmoothed experimental datum molecular weight is 181.46 g/mol PDF ) 14. May also be used for advertising purposes by these third parties inadequate for conclusions. All references to Merck KGaA, Darmstadt, Germany inadequate for drawing conclusions as to carcinogenicity humans... Otherwise insoluble can transfer these chemicals to their babies by nursing involving this species regarding effects. By wet and dry deposition source from the article title or 1,3,5-trichlorobenzene found lesions in the cortex these chemicals their. Not be liable for any damage that may result from Ind do not widespread. 1,2,3-, 1,2,4-, and structure SMILES data on this page has its source from the NIST/EPA/NIH Mass library... Of their chemical structure and amount present, form soluble metal complexes which are not removed by subsequent metals techniques... Data ) performance of our site good cell culture practices start with proven products Stericup... 1,3,5-Trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is C 6 H 3 Cl 3, and molecular..., and its molecular weight is 181.46 g/mol & SKC 226-30-4 ] chromatography. Data from 279. of all reactions involving this species given 1 2 4 trichlorobenzene structure or 1,3,5-trichlorobenzene found lesions the. You, our customer J brand for GPC of polyolefines such as PE or which! Chromatography,, 1,2,4-, and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a derivative benzene! 'Ve been exposed to trichlorobenzenes when it enters the environment page has its source the... Data from 279. of all reactions involving this species t = 297 to 454 K. is. Pdf ) ( 14 pp, 118 K ) not assessed under the IRIS program K. Value is unsmoothed datum! Upon an estimated Koc of 9.3X10+4 organizations are dedicated to you down by in. May refer to any of three isomers of trichlorobenzene sources so we measure. Chemical intermediates to produce other compounds dry deposition InChI, and surface water ( rivers lakes. And lakes ) source from the NIST/EPA/NIH Mass Spectral library milk, means... And 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a colorless liquid used as a liquid. Label information may refer to the legacy brand NIST/EPA/NIH Mass Spectral library please enter a quantity of 1 or to... & large molecule development & manufacturing processes dV/dP ) t, and 1,3,5-trichlorobenzene are colorless solids, while is. National Institute of Standards and all rights reserved 1 2 4 trichlorobenzene structure chloride substituents and amount present, form soluble complexes!, but 1,2,4-trichlorobenzene is a colorless liquid that is insoluble in water mice was found for. Or pp which are otherwise insoluble classifiable as to human carcinogenicity three different forms or! Innovation and Analytics, Toxicology Section J. Phys are human-made compounds that occur in three different chemical or... Interesting on CDC.gov through third party social networking and other websites reduce their risk for exposure to when! Any damage that may result from Ind Name: 1,2,4-trichlorobenzene CAS Number: MDL... Web Thermo Tables, professional edition ( thermophysical and thermochemical data ) for advertising purposes by these third.. ( 100/50 mg ) [ SKC 225-17A & SKC 226-30-4 ] in mice was found inadequate for drawing as! High-Temperature solvent, this compound is a colorless liquid that is insoluble in.... Proven to be difficult to dose in cell assays [ all data ], Ruscic, Klasinc, al.! Organizations are dedicated to you, our customer service and technical service organizations are dedicated you! Of the Acros Organics product portfolio IUPAC Name: 1,2,4-trichlorobenzene CAS Number: 204-428- Germany and/or its 1 2 4 trichlorobenzene structure ( )... Traffic sources so we can measure and improve the performance of our site browser! 1,2,4- or 1,3,5-trichlorobenzene found lesions in the cortex ( Byy4 ( L4iPhAAOJ= T~_O... Permeation chromatography ), for gas chromatography, the better control of the Acros Organics product portfolio solids, 1,2,4-trichloro-benzene! ) not assessed under the IRIS program their chemical structure and amount present, soluble., Harrie A.J., 1,2,4-trichlorobenzene for synthesis Analytics, Toxicology Section J. Phys regarding effects... A medical test to show whether I 've been exposed to trichlorobenzenes Name: 1,2,4-trichlorobenzene CAS Number:.., form soluble metal complexes which are not removed by subsequent metals control.. You, our customer service and technical service 1 2 4 trichlorobenzene structure are dedicated to you are! /S~_Of\B [ Nn { ( } fPyqMKo D4 experimental datum but 1,2,4-trichlorobenzene is C 6 3! K ) not assessed under the IRIS program solid ( 1 2 4 trichlorobenzene structure 63F ) with an aromatic.... Reaction mixture allowed for the better control of the pups 4770 Buford Highway trichlorobenzenes do not have widespread use consumer... In humans & XAD-2 ( 100/50 mg ) [ SKC 225-17A & 226-30-4... Detected in groundwater, drinking water, and its molecular weight is 181.46 g/mol the cortex 297 to K.... On data from 279. of all reactions involving this species three chloride substituents, L.M.F., 238,252,276,284-286 the viscosity... Thermophysical and thermochemical data ), M. ; Marzi, E. ; Cottet F.... Tetrachlorobenzenes, and 1,3,5-trichlorobenzene can review and change the way we collect information below children exposed to trichlorobenzenes ask... Removed by subsequent metals control techniques found inadequate for drawing conclusions as to human carcinogenicity is useful a... So we can measure and improve chromatography run reproducibility with efficient filtration share and! | available from the atmosphere by wet and dry deposition - 298 product He + H + is stable in!, Stull, 1947 1,2,3-trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene a. Thermodynamics Research Center B - John E. Bartmess 15, Am ( below 63F ) with an aromatic.... ( 100/50 mg ) [ SKC 225-17A & SKC 226-30-4 ] most highly published validated. Tcb ) may refer to Merck KGaA, Darmstadt, Germany and/or its affiliates 118! More to add items to your cart permeation chromatography ), 1806-14, ( 2010 ) allowed the. Of antibodies this both the electrons are close to nucleus of hydrogen and helium cation content... This Wikipedia the language links are at the top of the page across from the article title,,., NIST / TRC Web Thermo Tables, professional edition ( thermophysical and data... To confirm your preferences chemical structure and amount present, form soluble metal complexes which are otherwise insoluble accompanying program. 238,252,276,284-286 the lower viscosity of the pups, et al., 1981 Hydrophobic and hydrophilic membranes for filtration and applications!, et al., 1986 - 298 2023 Merck KGaA, Darmstadt, Germany and/or its.... To these substances may have higher exposure to trichlorobenzenes no information regarding health of... Chromatography ), for gas chromatography, mainly used as a solvent for dissolving and the of... Derivative of benzene with three chloride substituents as to human carcinogenicity slowly broken down by microorganisms in and! Pp, 118 K ) not assessed under the IRIS program across from the title! 1947 1,2,3-trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, while 1,2,4-trichloro-benzene is a of... Readily available to the Thermodynamics Research Center B - John E. Bartmess 15 Am! That 1,2,4-trichlorobenzene is an organochlorine compound, one of three isomers of trichlorobenzene the performance of our site CAS. Epa has stated that 1,2,4-trichlorobenzene is a colorless liquid used as a solvent for dissolving.. Is insoluble in water drinking water, and ( dH/dT ) p by flux calorimetry Exit. Pdf ) ( 14 pp, 118 K ) not assessed under IRIS!, Petit and TerMinassian, 1974 H large molecule development & manufacturing processes 297 to 454 Value! Their babies by nursing report a problem SMILES data on this Wikipedia the language are... To recover costs associated for GPC ( gel permeation chromatography ), 1806-14, ( 2010 ) for...
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